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Accueil > A propos du LPP > Communication > Actualités archivées > 2014 > René Pellat doctoral dissertation prize has been awarded this year to Ilya Marinov, a former PhD student at LPP

René Pellat doctoral dissertation prize has been awarded this year to Ilya Marinov, a former PhD student at LPP

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Two discharge modes
a) Slow (3-5 km/s) ’bush-like’ mode and b) Fast (20-50 km/s) ‘tree-like’ mode, demonstrate two distinct mechanisms of plasma formation in demineralized water [1-3]

In the first part of his thesis, Ilya Marinov studied the generation and propagation of nanosecond pulsed plasma in water. Very few teams in the world are able to characterize the plasma in liquid on time scale of a few nanoseconds. Mr. Marinov has developed the experimental device. By using nanosecond time-resolved imaging and spectroscopy the mechanisms of the discharge initiation in the liquid phase was studied in details for the first time. It has been shown that on time scale as short as nanosecond, the plasma is created directly in a dense medium. The initial pressures are shown to be extremely high, of the order of GPa, which gives very special properties to such plasmas.

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Plasma treatment of nude mice and immuno-histological sections of the epidermis, the dermis and the hypodermis for plasma exposure of 30, 60 et 90 s à 500 Hz [4]

In parallel, Ilya Marinov was the first PhD student at LPP to start working on the biomedical applications of plasmas. Application of cold plasmas to biology and medicine is a very new field of research, started less than a decade ago, developping very quickly. The most difficult step at the beginning is obviously to establish a common base of knowledge in physics and bio-medicine. During his thesis work, Ilya Marinov was strongly implied in development of two collaborations with bio- medical teams, one with a team from the St Louis Hopital on the potential use of plasmas in dermatology, and the other with a team from Institute Gustave Roussy , on the cellular response after exposure to plasma, as a novel therapy for cancer treatment.
After training in plasma physics at the University of Saint Petersburg and at Ecole Polytechnique in France, and after obtaining a doctoral degree in LPP (Paris Sud) , Ilya is currently working as a postdoc in the research laboratory of Institute Gustave Roussy , where he continues the study on the treatment of melanoma in vitro and in a preclinical model .

References :

  • Marinov I, Guaitella O, Rousseau A and Starikovskaia S M 2013 Cavitation in the vicinity of the high-voltage electrode as a key step of nanosecond breakdown in liquids Plasma Sources Sci. Technol. 22 6
  • Marinov I, Guaitella O, Rousseau A and Starikovskaia S M 2013 Modes of underwater discharge propagation in a series of nanosecond successive pulses J. Phys. D. Appl. Phys. 46 1–9
  • Marinov I, Starikovskaia S M and Rousseau A 2014 Dynamics of plasma evolution in nanosecond underwater discharge J. Phys. D. Appl. Phys.
  • Duval A, Marinov I, Bousquet G, Gapihan G, Svetlana M, Rousseau A and Janin A 2013 Cell Death Induced on Cell Cultures and Nude Mouse Skin by Non-Thermal , Nanosecond-Pulsed Generated Plasma PLoS One 8 1–11

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Tutelles : CNRS Ecole Polytechnique Sorbonne Université Université Paris Sud Observatoire de Paris Convention : CEA
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