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Home > Research > Low temperature plasmas > Plasmas medicine

Plasmas medicine

 What is plasma medicine?

  • Plasma medicine is highly multidisciplinary, bringing together engineering, plasma physics/chemistry, biology and clinical medicine
  • Cold plasmas for medical applications are close to room temperature and can hence be applied on living tissues
  • Reactive oxygen/nitrogen species from cold plasma interact with tumors thus enducing biological responses

 Research strategies

 Results on oral cavity

  • Partnership with LIB & CIMI/Hôpital de la Pitié Salpêtrière
  • Head and neck squamous cell carcinomas are the 6th most frequent cancer worldwide with 540000 new cases per year
  • Frequent relapse
    • 35-55% on 2 years
    • Severe prognosis (survival<20% at 10 years)
  • In vitro:TC-1 cell line has been treated by (i) direct plasma exposure (ii) PAMs and (iii) calibrated solutions containing nitrites, nitrates and H2O2
  • In vivo:
    • Assays on TC1 tumor model.
    • Increase of mice survival rate with 3 plasma treatments (15 min)
    • Burns & Toxicity is reduced using a dedicated plasma jet & monitoring skin temperature

 New activities in plasma medicine

  • Dermatology
    • Wound healing (severe burns & skin grafts)
    • Hôpital Percy, Clamart
  • Cholangiocarcinoma
    • Cancer from the biliary tree and liver
    • Centre de Recherche Saint-Antoine, Paris
  • Plasma sources & Engineering
    • Multi-channel jet
    • Plasma pulser

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Tutelles : CNRS Ecole Polytechnique Sorbonne Université Université Paris Sud Observatoire de Paris Convention : CEA
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