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Plasmas medicine
What is plasma medicine?
- Plasma medicine is highly multidisciplinary, bringing together engineering, plasma physics/chemistry, biology and clinical medicine
- Cold plasmas for medical applications are close to room temperature and can hence be applied on living tissues
- Reactive oxygen/nitrogen species from cold plasma interact with tumors thus enducing biological responses
Research strategies
Results on oral cavity
- Partnership with LIB & CIMI/Hôpital de la Pitié Salpêtrière
- Head and neck squamous cell carcinomas are the 6th most frequent cancer worldwide with 540000 new cases per year
- Frequent relapse
- 35-55% on 2 years
- Severe prognosis (survival<20% at 10 years)
- In vitro:TC-1 cell line has been treated by (i) direct plasma exposure (ii) PAMs and (iii) calibrated solutions containing nitrites, nitrates and H2O2
- In vivo:
- Assays on TC1 tumor model.
- Increase of mice survival rate with 3 plasma treatments (15 min)
- Burns & Toxicity is reduced using a dedicated plasma jet & monitoring skin temperature
New activities in plasma medicine
- Dermatology
- Wound healing (severe burns & skin grafts)
- Hôpital Percy, Clamart
- Cholangiocarcinoma
- Cancer from the biliary tree and liver
- Centre de Recherche Saint-Antoine, Paris
- Plasma sources & Engineering
- Multi-channel jet
- Plasma pulser
